Scientific Publications

  • Alves, J., et al., A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice. PLoS One, 2015. 10(12): p. e0144196.

  • Oliveira, L., et al., Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages. PLoS One, 2012. 7(1): p. e29963.

  • Madureira, P., et al., Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. PLoS Pathog, 2011. 7(11): p. e1002363.

  • Madureira, P., et al., Streptococcus agalactiae GAPDH is a virulence-associated immunomodulatory protein. J Immunol, 2007. 178(3): p. 1379-87.

Master Thesis

  • Tiago Pereira Rodrigues. Study the accessibility of IL-10 locus in a murine model of Neonatal Sepsis. MSc Thesis in Bioengineering, 2017. FEUP, University of Porto.

  • Cristiana Andreia Pereira Nogueira. Evaluation of the efficacy of a peptide-based vaccine (PNV1) against multi-resistant gram-negative bacteria in a neonatal mice model. MSc Thesis in Bioengineering, 2017. FEUP, University of Porto.

  • Filipa Gláucia Rodrigues Lemos. Study of the cellular and molecular mechanism associated with neonatal susceptibility to bacterial infections. MSc Thesis in Biochemistry, 2016. FCUP, University of Porto.


  • Pedro Madureira & Paula Ferreira (2015). Vaccine for Immunocompromised Hosts. WO2015/189422.

  • Pedro Madureira (2020). Immunogenic compositions. European Patent Application No. 20398008.1